Amfebutamone Hydrochloride31677-93-7盐酸an非他酮

Amfebutamone Hydrochloride31677-93-7盐酸an非他酮

盐酸an非他酮
分子式： C13H18ClNO.HCl        分子量：276.20
 
产品描述
Amfebutamone (Bupropion)是一种选择性去甲肾上腺素-多巴胺再摄取的抑制剂，IC50分别为6.5 和 3.4μM
靶点
          
IC50
          
生物活性
Amfebutamone (Bupropion) is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4µM for the reuptake of dopamine and norepinephrine, respectively. Its primary pharmacological action is Norepinephrine-dopamine reuptake inhibition. It binds selectively to the dopamine transporter, but its behavioural effects have often been attributed to its inhibition of norepinephrine reuptake. It also acts as a nicotinic acetylcholine receptor antagonist.
溶解性
DMSO 8 mg/mL，水 <1 mg/mL，乙醇 <1 mg/mL
稳定性
2年 -20°C粉状，6月-80°C溶于DMSO