VER 155008 1134156-31-2
VER-155008
分子式:C25H23Cl2N7O4分子量:556.4 (无水)
产品描述
VER 155008是新型的腺苷衍生的HSP70抑制剂,IC50为0.5 μM。
靶点
IC50
体外研究
VER-155002 is a small molecule, ATP-derivative inhibitor of HSP70 (IC50 = 500 nM). The compound inhibits proliferation of several colon and breast cancer cell lines, induces caspase dependent apoptosis in BT474 cells and down regulates expression of Her2 and Raf-1 in HCT116 cells.
体内研究
溶解性
DMSO >10 mg/mL
稳定性
2年 -20°C粉状,6月-80°C溶于DMSO